Lumbar disc herniation is a common and frequent disease, some research data show that 50 to 60% of the people in different periods of their lives have had back and leg pain, lumbar disc herniation in the population of the incidence rate of about 15%. The incidence of lumbar disc herniation in the population is about 15%. The number of lumbar disc herniation patients in the country is about 150 million. Traditional Chinese medicine treatment is conservative, including physiotherapy, massage, acupuncture, Chinese herbs, etc. In the late 1930s, Britain and New Zealand took the lead in carrying out laminectomy to remove the nucleus pulposus, due to the greater trauma and more complications, and then stepped into the minimally invasive treatment period in the 1960s, with the use of papaya enzyme and gelatinized enzyme injections to dissolve the nucleus pulposus; in the 1970s, Japan developed the percutaneous clamp nucleus pulposus removal technique, and in the 1980s, the United States developed the cut suction and laser ablation technique, etc. In the 1970s, Japan developed percutaneous clamp nucleus pulposus removal, and in the 1980s, the United States of America’s cutting suction and laser ablation made minimally invasive treatment more developed; in the mid-1990s, a new treatment method carried out in Italy – ozone (O2 ~ O3 gas mixture) injection of intervertebral discs and paravertebral space, which is more than the traditional method has the advantages of simple operation, less traumatic, safe, effective, cost-effective, and fast recovery. This technique is now generally recognized in Europe. Since 2000, our hospital has been the first in China to use percutaneous intravertebral disc ozone injection to treat lumbar disc herniation, and more than 2,000 patients with lumbar disc herniation have received ozone treatment in our hospital. The follow-up period is from 3 to 72 months, and the total effective rate is 82.25% according to the MacNab evaluation standard, and no serious complications occurred in all the patients. This procedure was highly evaluated by domestic counterparts, and the technology was firstly introduced in June 2002 in the National Interventional Symposium on Lumbar Herniated Disc, and Prof. Marco Leonardi from Italy was invited to give lectures, and at the same time, Prof. He Xiaofeng of our hospital, together with Prof. Marco, carried out the first case of ozone treatment for cervical disc herniation via anterior approach in our hospital. end of 2004 With the introduction of Italian Ozoneline medical ozone generator, more hospitals joined in the treatment, and the second and third national ozone treatment seminars for cervical and lumbar intervertebral disc herniation were held in 2005 and 2008, in which nearly one hundred specialists from different parts of the country introduced the successful experience of the treatment. So far, four national seminars on ozone therapy for lumbar intervertebral disc herniation have been held successively. More than 100 regional seminars have been held in various provinces and cities, greatly promoting the popularization of ozone treatment of lumbar intervertebral disc herniation. Fig. 1 Prolapsed intervertebral disc Fig. 2 Retraction in three months after operation