Whether Enalapril Maleate Folic Acid Tablets need to be used in combination with other drugs needs to be assessed according to the patient’s disease condition, blood pressure control, etc. If the blood pressure control is not good with the medication alone, other antihypertensive drugs, such as hydrochlorothiazide, metoprolol, etc., can be used in combination. Enalapril Maleate Folic Acid Tablets are used for the treatment of essential hypertension accompanied by elevated plasma homocysteine levels. When the patient’s blood pressure is not well controlled with enalapril maleate folic acid tablets, combined with the patient’s condition and comorbidities, calcium antagonists such as amlodipine tablets, diuretics such as hydrochlorothiazide, and beta-blockers such as metoprolol can be used in combination. Enalapril Maleate Folic Acid Tablets cannot be used in patients with angiotensin-converting enzyme inhibitor therapy for the development of angioneurotic edema, as well as patients with hereditary or spontaneous angioneurotic edema, and should be used with caution in those with severely impaired renal function. It is contraindicated in pregnant women and used with caution in lactating women. Adverse reactions such as edema, dizziness, headache, dry cough, epigastric discomfort, nausea, palpitations, skin rash may occur after use. It is recommended that patients consult a physician before using the drug, and when a combination of drugs is needed, it should be taken under the guidance of a physician and in accordance with medical advice.