Whether an enlarged thyroid gland can heal on its own should be analyzed on a case-by-case basis. Most patients with physiologic goiter have the possibility of self-healing, but some patients with pathologic goiter cannot be self-healed. 1. Physiological: For children during puberty, pregnancy or menopause, these people have a higher demand for thyroxine, which can lead to diffuse enlargement of the thyroid gland. Generally, after the above stages, the demand for thyroxine returns to normal, and the enlargement of the thyroid gland may be cured by itself. 2. Pathological: However, in patients with iodine deficiency, nodular goiter, thyroid adenoma and goiter caused by thyroid cancer, the goiter usually cannot be cured by itself, and exogenous supplementation of levothyroxine, surgery, etc., is often needed to make the goiter subside. Therefore, patients with enlarged thyroid should go to the hospital in time for a complete examination to clarify the cause of the goiter and then undergo targeted treatment according to the cause.