Submucosal bulge of the esophagus 29 cm and 34 cm from the incisors is a space-occupying lesion of the esophagus observed during gastroscopy, which usually requires further examination by ultrasound endoscopy. Esophageal submucosal bulges are lesions of submucosal origin generally may be associated with esophageal inflammation, smooth muscle tumors, and other causes. During the first gastroscopy, if the doctor finds a submucosal bulge, he or she will carefully observe the size of the bulge and touch it with a biopsy forceps to observe the mobility and texture. Because submucosal bulges in the esophagus may be smooth muscle tumors or esophageal gliomas, etc., elective ultrasound endoscopy is recommended to clarify the condition. Ultrasound endoscopy can visualize the extent of the lesion as well as the origin of the bulging lesion, clarify the nature of the bulge, and make a clear choice of how to treat it.