Acne generally refers to acne, acne becomes red, swollen and hard need to use topical medication, oral medication treatment, please follow the doctor’s instructions. 1. Topical medication: acne that is mainly red, swollen and painful can be treated with antibiotics such as clindamycin cream, erythromycin ointment, fusidic acid cream, or benzoyl peroxide gel, azelaic acid, and so on, as prescribed by the doctor. 2. Oral medication: Minocycline, doxycycline and other tetracyclines can be taken orally as prescribed by the doctor, which has the effect of anti-inflammatory and inhibiting Propionibacterium acnes. For acne with nodules and cysts, oral isotretinoin is also needed. Acne becomes red, swollen and hard usually suggests that the local inflammatory reaction is more obvious, it is recommended that the patient consult a doctor in a timely manner, follow the doctor’s instructions to standardize the use of medication, and avoid local extrusion.