Blood creatinine 139μmoI/L, the method of lowering creatinine mainly depends on the cause of elevated creatinine. Elevated creatinine may be caused by physiological factors, but also may be pathologic, such as drug-induced renal injury, glomerulonephritis, urinary tract obstruction, etc. Different causes of different treatment methods. 1. Physiological increase: If the blood creatinine 139μmoI/L is physiological increase, such as consuming too much meat, strenuous exercise, etc., generally continue to observe, can not give any treatment, and most of them can be restored to normal after removing the causative factors. 2. Drug-induced renal damage: the use of drugs leading to renal injury, need to stop immediately, continue to observe, most of the blood creatinine can be returned to normal. 3. Glomerulonephritis: primary glomerulonephritis with elevated creatinine usually indicates renal function injury, usually can choose hormone and immunosuppressant treatment as prescribed by doctor, such as prednisone, cyclophosphamide, etc.; if the elevated creatinine is caused by other diseases, such as diabetes mellitus, hepatitis B, and purpura allergic, etc., it is necessary to actively treat the primary disease to prevent the disease from further progress. 4. Urinary system obstruction: stones and tumors in the urinary system can lead to elevated blood creatinine, and it is necessary to clarify the cause and release the obstruction as soon as possible. If the blood creatinine is found to be elevated, it is necessary to consult a doctor as soon as possible to find out the cause and carry out standardized treatment according to the doctor’s instructions.