Fire at the end of the nose refers to symptoms such as inflammation, redness and swelling of the nose caused by TCM. Chinese medicine refers to the disease caused by external wind evil and internal stagnation. Allergic rhinitis, called immune hyperactivity in Western medicine, is a lung Yin deficiency and Yang hyperactivity in Chinese medicine, while the nose passes through the lungs and fire comes out of the nose. So, what causes fire at the end of the nose? The following are the causes of nasal fire: 1. Genetic factors A family history of allergic reactions predisposes people to this disease. The patient’s family has a history of asthma, urticaria or drug allergies. Previously, this patient was called an atopic individual, whose body’s ability to produce IgE antibodies is higher than normal. However, in recent years, some authors have found that there is no significant difference in the incidence between twins and the general population. 2. Susceptibility of nasal mucosa Susceptibility arises from the frequent stimulation of antigenic substances, but the degree of susceptibility depends on the number of mast cells and basophils in the nasal mucosa and the ability to release chemical mediators. It has been confirmed that the number of these cells in the nasal mucosa of patients with allergic rhinitis is not only higher than normal, but also has a strong ability to release chemical mediators. 3, antigenic material The antigenic material that stimulates the body to produce IgE antibodies is called allergens. The allergen substance re-entered the nasal mucosa and combined with the corresponding IgE and caused a metamorphic reaction. The allergens that cause this disease are divided into two categories: inhalation and food, according to the way they enter the body.