Women who do not live together for a long time may cause symptoms such as endocrine disruption, reduced hormone secretion or reduced self-purification. 1. endocrine disorders: endocrine disorders is the body’s regulatory system, often cause face spots, yellow skin, breast swelling, mood, weight and other changes, if women do not have sex for a long time, there is a high probability that will lead to abnormal secretion of estrogen in the body of the woman, resulting in disorders of the endocrine system. 2. Reduced hormone secretion: women’s menstruation has a certain relationship with women’s estrogen, if the long-term absence of sexual intercourse may reduce women’s estrogen secretion, which may lead to premature ovarian failure, delayed menstruation, menstruation delay, dysmenorrhea, and other symptoms, and even enter menopause early. 3. Reduced self-cleaning ability: the vagina will secrete a mucus, this mucus can play the role of sterilization, there are a large number of bacteria in the female vagina, if there is no sex for a long time, this mucus will be secreted too little or not normal, may cause female vaginitis. Usually pay more attention to rest, more exercise, couples sex life is reasonable, do not excessive.