Before using pancreatic kininogenase injection, add 1.5 ml of sterilized water for injection to dissolve, intramuscular injection of 10~40 units a day, once a day or every other day, should be standardized under the guidance of a doctor. Pancreatic kininogenase injection is a vasodilator, can improve microcirculation, commonly used in diabetic nephropathy, peripheral neuropathy, retinopathy, ischemic cerebrovascular disease and so on. Common adverse reactions include rash, skin itching, and tiredness, which disappear after stopping the drug. It is contraindicated in people who are allergic to this drug, cerebral hemorrhage and other bleeding disorders in the acute stage. Precautions are not clear, and the use of the drug in pregnant and lactating women is not clear. This drug should not be used simultaneously with protease inhibitors, and has a synergistic effect with angiotensin-converting enzyme inhibitors. If you need to use this drug, it should be used reasonably under the guidance of a doctor, and should not be taken blindly to avoid adverse reactions.