The prevalence of schizophrenia in the normal population is 1%; the prevalence of schizophrenia in children born to a couple with one partner suffering from schizophrenia is 1/10; the prevalence of schizophrenia in children born to a couple with both partners suffering from schizophrenia is 4/10. Therefore, the prevalence of schizophrenia in children born to a couple with one partner suffering from schizophrenia is 10 times higher than the normal population, and the prevalence of schizophrenia in children born to a couple with both partners suffering from schizophrenia is 40 times higher than the normal population. Therefore, we believe that both men and women with schizophrenia should not get married, and if they are married, they should not have children. If one spouse has schizophrenia and the other is mentally normal, they can get married. As for childbirth, some parents believe that since the heritability rate is 10 times higher than that of normal people, the risk of heredity to the next generation is too great, and since it is already difficult for the patient to take care of himself/herself because of his/her illness, it would be too much for the family to bear the burden if he/she were to pass it on to the next generation. However, not to have children is not only an important decision, but also seriously affect the way of life in the second half of life, watching neighbors add children, hold grandchildren, pick up kindergarten, pick up elementary school, their own free hair, see the neighboring children to see their parents on New Year’s holidays, their own home is cold and quiet, there is a kind of unexplainable loneliness, to the twilight years, one old partner died first, another old partner became a widowed elderly. Is afraid to have children with 1/10 chance of disease, or afraid of old age 100% do five households, patients can choose for themselves. Yu Dongshan believes that it is better to risk the 1/10th chance of having a child with the disease than to be a permanent household in old age. What’s more, schizophrenia patients who are in remission to a level where they can get married and have children should be among those in better remission. Even if their children are unfortunate enough to hit that 1/10 chance of developing schizophrenia in the future, their symptoms, outcome and prognosis are similar to those of genetic parties, and theoretically speaking, the prognosis is not that bad.