In patients with chronic viral hepatitis B, if the patient has a blood test for hepatitis B triple system, it indicates that the patient is positive for hepatitis B surface antigen, positive for hepatitis B E antigen and positive for hepatitis B core antibody. If the patient’s blood is positive for these three systems, he or she is most often considered to be a major triple-positive. For patients with major triple-positive, if the patient’s further blood test liver function indicates elevated glutathione and glutamic oxalacetic aminotransferase, and the hepatitis B DNA results indicate that the patient’s virus is replicating, the patient is considered to be in the window of viral replication, and it is generally recommended that the patient actively consider antiviral treatment. You can consider oral antiviral drugs, such as tenofovir, entecavir and other related antiviral drugs for active treatment. For patients with hepatitis combined with cirrhosis, or liver fibrosis, patients should not stop taking oral antiviral drugs, which may lead to withdrawal reactions and the possibility of further liver failure. In addition, for some patients, you can also actively consider interferon injections to antiviral therapy, generally need to inject six months to a year or so, the patient’s viral replication will tend to stabilize, the patient’s liver function will also gradually recover better.