The ingredient of Lodinexin is Benazepril Hydrochloride, which belongs to angiotensin-converting enzyme inhibitors, and is mainly used in the treatment of hypertension and cardiac insufficiency in clinical practice. The side effect of irritating dry cough may occur during administration. Once the side effect is not tolerated, it needs to be replaced with angiotensin II receptor blocker, representative drugs include valsartan and irbesartan. During the treatment of hypertension, calcium antagonists and beta-blockers can be selectively combined depending on whether there is a combination of coronary artery disease or the presence of tachycardia, and hypotension should be prevented when combining drugs. In the treatment of cardiac insufficiency, in addition to the role of vasodilatation, the more important role is to prevent ventricular remodeling, according to the condition of the selective combination of beta-blockers, diuretics, the application of the process of close monitoring of ions, to prevent ionic disorders.