The pain relief methods for periodontitis are as follows: 1. Removal of infectious substances around the teeth: such as calculus and other rough tissues, through periodontal rinsing, anti-inflammatory, to achieve the effect of pain relief; 2. Oral anti-inflammatory drugs: oral anti-inflammatory drugs, which can be used for pain relief purposes, such as cephalosporins, tetracyclines, and more clinically used drugs are tetracyclines. Clinically, the drug can be injected into the periodontal pocket to avoid resorption of bone around the tooth caused by periodontitis. Pay attention to the history of drug allergy when applying drugs.