Alcohol dependence syndrome is the specific psychological state of the body’s craving for alcohol due to repeated or persistent drinking, and the specific psychological response that occurs when drinking is reduced or stopped, also known as withdrawal syndrome. The core manifestations are a strong internal drive to use alcohol, resulting in impaired ability to control alcohol use, prioritization of alcohol use over other activities, and continued use despite the presence of harm or adverse outcomes from drinking. Alcohol dependence is characterized by the following: first, compulsive alcohol-seeking behavior, because the inner desire for alcohol is so important in life that it leads to compulsive alcohol-seeking, which cannot be controlled by the will. The second is that the rhythm of life is disrupted by the fact that drinking is the center of life and there is nothing to do all day. The third, unplanned drinking, without a time pattern, usually manifested as morning drinking, drinking before bedtime, drinking on an empty stomach, and even waking up at night to drink. The fourth, attempting to quit drinking, alcohol dependence patients can realize that their behavior is wrong, have quit drinking behavior but often end up in failure, and keep relapsing and cannot control. The fifth one, psychological dependence, alcohol dependence patients will be irritable, tired and unrefreshed without drinking alcohol, but after drinking alcohol, they are energetic and treat alcohol as medicine. The sixth one, forgetfulness, is the most common syndrome of alcohol dependence patients, amnesia syndrome, which is mainly characterized by loss of memory. The seventh, withdrawal symptoms, a series of physical discomfort will appear after sudden drinking, manifested as headache, insomnia, nausea, vomiting, limb twitching, etc. These symptoms are unbearable for patients and become important reasons to drink again.