Inability to open the eyes is more commonly caused by visual fatigue, due to long hours of watching TV, watching cell phones, resulting in visual fatigue, may not be able to open the eyes, accompanied by tearing. It can also be seen in conjunctivitis and keratitis, and the patient will be accompanied by tearing and pain. In the case of glaucoma, the patient may experience eye pain and headaches, and ophthalmology consultation is recommended when necessary. Inability to open the eyes also suggests neurological disorders, more commonly myasthenia gravis, the patient may present with ocular myasthenia gravis, which is characterized by upper eyelid lifting difficulties, and the patient may be given a neostigmine test if necessary. Intracranial space-occupying diseases can also cause damage to the eye muscles, and the patient may also present with an inability to lift the upper eyelid and open the eye, for which neurology consultation is recommended.