Dead hard skin on the soles of the feet may be a symptom caused by callus, corns, plantar warts and other diseases. Patients can under the guidance of the doctor for general treatment, drug treatment, physical therapy, surgical treatment and so on. 1. callus: callus is the keratosis pilaris damage caused by pressure or friction on the skin of the foot. It is mainly manifested as thickened keratinized patches, generally yellowish in color. Callus generally do not need treatment, patients need to pay attention to reduce local friction in daily life. Patients with more serious symptoms can use salicylic acid ointment, urea ointment and other local topical drugs. 2. Corns: patients can appear parallel to the skin surface or elevated keratinous plugs, and there is obvious pain when pressure. Patients can use salicylic acid ointment, corns cream and other local topical drugs, can also be removed by liquid nitrogen freezing, laser treatment and other physical therapy. For larger corns, corns can also be excavated. 3. metatarsal warts: metatarsal warts are caused by human papilloma virus infection of the plantar region of the foot due to the proliferation of patients in the beginning of the symptoms of hard skin. Patients can use imiquimod ointment, fluorouracil ointment and other topical drugs to apply. If necessary, they can be removed by physical methods such as laser or freezing. It should be noted that all of the above drugs should be used under the guidance of a doctor, and patients should not use them on their own to avoid delaying the condition. Patients with dead hard skin on the soles of their feet should go to the hospital in time and under the guidance of doctors for regular treatment.