Methylcobalamin can be taken on an empty stomach, and it will not have any stimulating effect on the gastrointestinal tract, and the effect of taking methylcobalamin on an empty stomach will be better absorbed. Methylcobalamin is an endogenous vitamin B12, which is widely existed in human blood and bone marrow. The main function of methylcobalamin is to promote the generation and regrowth of nerve myelin, so it can be used for the repair of peripheral nerves. In clinical practice, methylcobalamin is mainly applied to some neurological diseases, such as peripheral facial nerve palsy, which requires oral administration of methylcobalamin for treatment. If the peripheral nerve damage is caused by diabetes, methylcobalamin can be taken orally to promote the repair of nerve and myelin sheath, thus improving the patient’s symptoms such as limb numbness. If there is damage to the brain nerve, resulting in numbness of the limbs, etc., oral methylcobalamin can also be taken to improve the symptoms.