Olmesartan ester tablets is a kind of angiotensin II antagonist, edema during the use of medication, may be an adverse drug reaction, heart failure, according to the cause of the discontinuation of the drug, as well as general treatment, drug treatment and other measures. 1. Adverse drug reactions: most patients taking olmesartan ester tablets may appear edema, which is a normal reaction to the drug, if only slight edema, generally no special treatment, adhere to the medication can be relieved on their own, but to regularly monitor blood pressure. 2. Heart failure: long-term use of olmesartan ester tablets, edema symptoms can not be eliminated, and the symptoms will gradually aggravate, considering the use of the drug during the emergence of heart failure. This product should be discontinued as soon as possible, and then switch to other types of antihypertensive drug therapy, such as amlodipine, nifedipine and so on. If heart failure is severe, oral diuretics, such as furosemide, are required. If the patient is allergic to any component of Olmesartan Tablet, or if there is renal artery stenosis or renal insufficiency, it needs to be prohibited. Prolonged use of the drug may cause diarrhea, headache, hematuria and other symptoms, which will be relieved after discontinuation of use. The specific medication regimen should be carried out in strict compliance with the physician’s instructions.