Tg ≥1ng/ml suggests recurrence of thyroid cancer, and the diagnosis of recurrence also requires imaging and pathologic diagnosis, etc.
After total resection of thyroid cancer, levothyroxine tablets are usually taken to inhibit thyroid stimulating hormone, and thyroglobulin is in a state of inhibition at this time. Thyroglobulin is then suppressed, and it is necessary to stop taking levothyroxine for 4 weeks or to be stimulated by thyrotropin before the globulin is reviewed. Typically, globulin needs to be <0.2 ng/ml in the suppressed state and <1 ng/ml in the stimulated state.
Thyroglobulin >1ng/ml suggests the possibility of recurrent or residual thyroid cancer. However, only elevated thyroglobulin cannot diagnose recurrence, and the diagnosis of recurrence also needs the results of experimental, imaging and pathological examinations, such as neck ultrasound, enhanced CT, MRI, ultrasound-guided puncture biopsy or excisional biopsy.
It is recommended that postoperative thyroid cancer patients should be followed up regularly, and if there are abnormal results, they should follow the doctor’s instructions for further examination and treatment.