What causes large blisters on the legs?

Common causes of large blisters on the legs (medically known as blisters) include eczema and pemphigus.
1. Eczema:The cause of eczema is currently unknown, but if you wear some poorly ventilated pants for a long time, resulting in the skin being in a hot and humid environment for a long period of time, it may cause eczema, which manifests itself as erythema, pimples, papules, blisters, itchiness, vesicles and other symptoms.
2. Pemphigus:Pemphigus is a group of autoimmune chronic herpetic dermatosis caused by epidermal cell laxity, the etiology of which is unknown, and it is currently believed that this disease is mainly an organ-specific autoimmune disease mediated by organ-specific autoantibodies-anti-pemphigus antigen antibodies. It is characterized by erythema, blisters, maculopapularity, itching, tingling and other symptoms.
It is recommended that patients go to the dermatology department of regular hospitals, follow the doctor’s instructions to clarify the diagnosis, and actively treat the disease to avoid delaying the condition.