[Abstract] Objective To investigate the clinical feasibility and efficacy of single-channel laparoscopy-assisted peritoneal dialysis tube placement. Methods In 13 patients with chronic renal failure who had no history of preoperative laparotomy, a 16 Fr laparotomy channel was established in the lower abdomen under local anesthesia using a minimally invasive percutaneous puncture technique, a 5-mm diameter laparoscope was used to enter the abdominal cavity for positioning, and a Swan-neck peritoneal dialysis tube was placed into the cystorectal fossa or uterine rectal fossa at one end through a disposable skinning sheath, and a subcutaneous tunnel was established at the proximal end and drained through a hole poked in the left lower abdomen. Results All peritoneal dialysis tubes were placed successfully, with a mean operative time of 28±8 min, minimal intraoperative bleeding, and discharge from the hospital 3-7 days after surgery. The longest one has been followed up for 12 months, and no complications such as floating tube, leakage, blockage, bleeding, or infection were observed. Conclusion Single-channel laparoscopic-assisted peritoneal dialysis tube placement is a new method of tube placement with precise positioning, safety and reliability, and few complications. 【Key words】Laparoscopy;peritoneal dialysis tubing;