The main treatment for epilepsy is surgery, which has brought good news to epilepsy patients, but we should not blindly believe in surgery and think that surgical treatment for epilepsy can be a complete solution, because any treatment is not 100% effective. The following is a review of the main factors that influence the effectiveness of surgical treatment, and we hope that it will help epilepsy patients to choose the right treatment. If the epileptogenic foci are extensive and numerous, and they are in the functional area, it is very difficult to achieve the goal of radical treatment through surgery anyway. If the epileptogenic foci are limited and mostly not in functional areas, then the surgical results should be very good and most patients can be cured by surgery. Therefore, the assessment of the epileptogenic focus is more important than the surgery itself. Only when the location and distribution of the epileptogenic focus are clearly defined, and whether it is in the functional area or not, can the surgery provide a clear direction to achieve the goal of “precise guidance and reasonable strike”, and achieve good results. Epilepsy surgery is a systematic and complex process, and a series of comprehensive preoperative evaluations are required to clarify the diagnosis of the epileptogenic focus. These evaluations include brain electrophysiology, structural brain examination, and a detailed clinical history of seizures. In addition, a neuropsychological evaluation is performed preoperatively. Only when the electrophysiological examination, imaging and clinical data are consistent should surgery be considered. In order to achieve the purpose of “precise guidance and reasonable strike”, the following conditions must be met: 1. The Neurosurgery-Epilepsy Center of Fuzhou General Hospital is equipped with 9 sets of the latest 192, 128 and 32 conductor long-range video EEG monitoring systems from Japan Photoelectric Industry Co. In addition, advanced evoked potential-EEG monitoring system is equipped for intraoperative neurological function monitoring and ECoG localization. The center has priority access to advanced equipment such as SPECT, PETCT and 3.0T MRI of the hospital. The level of equipment is no less than that of epilepsy centers in developed countries. Such advanced technical equipment provides a strong backing for the clear localization of epileptic foci. 2, strong medical team: good technical equipment, but also must have a good medical team, for the medical team engaged in epilepsy treatment must have epilepsy internal medicine, epilepsy surgery, electroencephalography, neuroimaging, neuropathology and other multidisciplinary professional and technical personnel, only these talents cooperate fully to provide the most appropriate diagnosis and treatment services for epileptic patients. The Neurosurgery-Epilepsy Center of Fuzhou General Hospital is such an excellent team that brings together a variety of talents. The center’s daily work is presided over by Dr. Yang Pengfan, a returned scholar, and assisted by an EEG specialist who is qualified to diagnose EEG in Asia. We have invited Professor Hori from Tokyo Women’s Medical University Brain Neurology Center, Professor Winkler from Munich University Epilepsy Center, Germany, and Professor Scherg, an EEG computer analysis specialist from MEGIS, Germany, as consultants to the center. The Center has established long-term scientific collaboration with Tokyo Women’s Medical University Brain Neurology Center and Munich University Epilepsy Center, and has been identified by MEGIS EEG software company in Germany as a training base for BESA software in China. For such a team with international background in epilepsy diagnosis and treatment, they have the most advanced treatment concept and can provide the best and most appropriate treatment plan for epilepsy patients. Since its establishment in 2004, the Epilepsy Center of Fuzhou General Hospital has confirmed the diagnosis of tens of thousands of epileptic patients, routinely completing 6~10 epilepsy surgeries per week, and has so far done surgical treatment for more than 2000 cases of refractory epileptic patients suitable for surgery, including intracranial electrodes We have performed more than 300 intracranial electrode implantation surgeries (as of November 2010), with a satisfactory postoperative epilepsy control rate of more than 85%, which has won the general recognition and trust of our colleagues and patients at home and abroad. In summary, the epileptogenic foci of epileptic patients, the technical equipment of medical institutions, the medical team engaged in epilepsy diagnosis and treatment, and the surgical skills and clinical experience of surgeons are the main factors determining the surgical outcome.