Whether atrial fibrillation is serious or not depends on the control of the condition. If the condition is stabilized, the patient can be followed up; if the condition is not well controlled, the condition is more serious and can be complicated by life-threatening complications such as stroke. Whether atrial fibrillation is serious or not depends on the drug treatment of patients with atrial fibrillation. If the atrial fibrillation is well controlled, patients can have regular checkups; if atrial fibrillation is poorly controlled by drug treatment, or even if anticoagulant drugs are not used in a standardized way, it can produce a variety of symptoms or complications that can endanger the patients’ lives and health. Atrial fibrillation, or atrial fibrillation, refers to the loss of regular and orderly activity of the atrium, which is replaced by a serious disturbance of the electrical activity of the atrium, i.e., rapid and disorderly flutter waves. Patients with atrial fibrillation may suffer from angina pectoris and congestive heart failure. At the same time, atrial fibrillation complicates the risk of thromboembolism, especially the complication of cerebral thromboembolism, which can often jeopardize the life of the patient, and seriously affect the quality of survival of the patient. Patients with atrial fibrillation should be actively engaged in long-term comprehensive treatment, applying anticoagulation therapy such as rivaroxaban to prevent thromboembolism. At the same time, quinidine, amiodarone, etc. can be applied to regain and maintain sinus rhythm and control ventricular rate treatment. The use of specific drugs should be under the guidance of a doctor. If the diagnosis of atrial fibrillation is confirmed, it is recommended that the patient consult a doctor in a timely manner and standardize the treatment according to the doctor’s instructions.