Pain next to the cheek while eating may be caused by masticatory muscle pain, TMJ synovitis and other diseases, treatment includes oral painkillers, local closure, physical therapy, etc., as follows. 1. Chewing muscle pain: local moist hot compresses, cold compresses, physiotherapy, taking non-steroidal anti-inflammatory analgesic drugs, such as diclofenac sodium, meloxicam, etc., and if necessary, use lidocaine to close the pressure point for treatment. 2. Synovitis of temporomandibular joint: oral analgesic drugs, such as diclofenac sodium, meloxicam, etc., supplemented with physical therapy, if there is no obvious effect, you can use prednisolone suspension to add lidocaine for joint closure treatment. The above drugs should be used under the guidance of a doctor, there may be other reasons for the pain next to the cheek when eating, it is recommended to go to the hospital in a timely manner, to clarify the cause of the disease for targeted treatment.