Pancreatic hyperdense shadow calcification is mainly divided into physiological calcification and pathological calcification, with different hazards due to different reasons, which may cause cancer or not affect the life expectancy. 1. Physiological calcification: it is less harmful to human body, most patients do not have obvious symptoms, and it will be found through examination. If the symptoms are not obvious, no special treatment is needed. Generally, it will not affect the life expectancy and will not cause other adverse reactions. 2. Pathological calcification: usually related to chronic pancreatitis, indigestion and other factors, if not treated in time, it will affect the gastrointestinal peristalsis, and patients will often have flatulence and loss of appetite, which will have a greater impact on the quality of life. If it belongs to precancerous lesions and is not treated in time, it is likely to turn into pancreatic cancer, and it will threaten the patient’s life and shorten the survival time. If calcification of pancreatic hyperdense shadow is found, it is recommended to consult the doctor in time and target treatment according to the diagnosis.