The treatment of chronic lymphocytic leukemia is divided into medication and surgery, the monthly cost of medication is around 2,000 to 3,000 yuan, while surgery costs around 200,000 to 250,000 yuan, depending on different regions and levels of hospitals, the price is also different. 1. In the early stage of the disease, if the patient does not suffer from infection fever or bleeding, the main treatment is the application of ibrutinib targeted therapy, the current monthly cost is around 2,000 to 3,000 yuan, and some hospitals may have a slightly higher cost, and in the stage of intensive treatment after remission, the treatment needs to be carried out according to the patient’s physical condition. 2. Chronic lymphocytic leukemia can be treated with bone marrow transplantation, which costs about 200,000 to 250,000 yuan for an average patient. The price varies according to the treatment method, different regions and levels of hospitals. Medication costs around 2,000 to 3,000 dollars per month and surgery costs around 200,000 to 250,000 dollars. The treatment should be carried out under the supervision of a physician.