In most cases, lung cancer metastasized to adrenal glands will not show obvious symptoms, but some patients may have back and abdominal pain, as well as adrenal insufficiency, high blood pressure and other symptoms. As adrenal glands are located in the upper abdomen and close to the back, tumor metastasis to adrenal glands will often cause patients’ upper abdomen and back pain. Lung cancer metastasis to adrenal glands may cause adrenal insufficiency, which manifests as weakness, extreme weakness, severe hypotension, hypoglycemia, renal insufficiency, hyponatremia, and hyperkalemia. In addition, invasion or stimulation of the adrenal glands can cause persistent hypertension or sudden hypertension. Besides the above symptoms, patients will also have symptoms of lung cancer itself such as hemoptysis and chest pain. For patients with lung cancer metastasis, it is necessary to actively treat the primary tumor, and for patients with adrenal metastasis, adrenalectomy, interventional therapy, chemotherapy and so on can be carried out if necessary. It is recommended to go to regular hospitals for comprehensive assessment of the condition, follow the doctor’s instructions to cooperate with the treatment, and choose the appropriate treatment plan to avoid delaying the condition.