Pustules on the face may be caused by acne, folliculitis or impetigo, and patients are advised to treat them with medication after clarifying the specific cause under the guidance of a doctor. 1. Acne: When bacterial infection occurs in acne, pustular changes may occur. At this time, patients can use topical antibiotic drugs, such as mupirocin ointment, fusidic acid ointment and so on. At the same time, topical retinoids such as adapalene gel and tazarotene gel can be used. 2. Folliculitis: Folliculitis is a purulent inflammation of the skin, confined to the area of the mouth of the hair follicle. Antibiotic drugs such as topical mupirocin can be used in the treatment. You can also take oral cephalosporin or penicillin antibiotics. 3. Impetigo: Impetigo is mainly caused by Staphylococcus aureus infection, in the treatment can be used externally with glycerine lotion, at the same time can be used externally with mupirocin ointment, fusidic acid cream and other antibiotic drugs. For patients with pustules on the face, it is recommended to go to the regular hospital in time for examination, clear diagnosis, symptomatic treatment, the above drugs need to be used in accordance with medical advice.