Surface antigen generally refers to the surface antigen of hepatitis B. Hepatitis B surface antigen 6000UI/ml is a quantitative test value, which does not strictly indicate the degree of severity, and it is necessary to cooperate with other tests to determine. Surface antigen generally refers to the serum markers of hepatitis B virus infection, when it reaches 6000UI/ml, then it is recommended to confirm the diagnosis with the alpha-fetoprotein test, liver function, abdominal ultrasound, and hepatitis B virus nucleic acid test. If the patient’s liver function and abdominal ultrasound are normal, it indicates that the patient is in the tolerance period of hepatitis B immunity, and at this time, observation and treatment can be carried out. If the liver function is obviously abnormal for more than six months, and the test of hepatitis B virus nucleic acid is high, it indicates that the patient is infected with hepatitis B virus, and it generally suggests that the patient enters the clearing period of hepatitis B immunity, which is a serious situation, and it is important to cooperate with the treatment as soon as possible with the doctor’s advice and guidance.