A drop in human chorionic gonadotropin at six weeks of pregnancy does not necessarily mean that the fetus has stopped labor, but it can also be due to ectopic pregnancy, biochemical pregnancy and other reasons. Human chorionic gonadotropin is a glycoprotein secreted by the trophoblast cells of the placenta and is important for early pregnancy diagnosis. It has been shown that there are many reasons for a drop in human chorionic gonadotropin at six weeks’ gestation, and that it does not necessarily mean that the pregnancy has been terminated. Fetal arrest occurs in relation to chromosomal abnormalities of the embryo, uterine malformations, luteal insufficiency, etc. Most patients have no discomfort, but may experience a small amount of vaginal bleeding. Apart from that, six weeks of pregnancy with decreased human chorionic gonadotropin may also be ectopic pregnancy. Common causes include tubal inflammation, dysplasia, pelvic inflammatory disease, contraceptive failure, endocrine abnormalities, etc. Typical symptoms are menopause, abdominal pain and irregular vaginal bleeding. Secondly, it is also necessary to consider a biochemical pregnancy, which may be related to polycystic ovary syndrome, poor sperm quality and other reasons, usually without obvious abnormal manifestations. It is recommended to visit the hospital in time to clarify the specific cause.