I often hear patients ask about the possibility of having a gastroscopy without intubation to check for gastrointestinal diseases. From time to time, TV, internet and other media claim that you can have a non-intubated gastroscopy for 50-60 RMB, which is painless and provides a comprehensive examination of gastrointestinal, liver and gallbladder diseases. Is this really true? The answer is no! Because the socially prevalent gastroscopy without intubation is actually an ultrasound. Ultrasound is a non-invasive, indirect imaging test. It has a high diagnostic value for the diagnosis of liver, gallbladder, spleen, pancreas, kidney and other substantive organ disorders; the diagnosis of gastrointestinal cavity organ disorders (such as esophagus, stomach, duodenum, large intestine) is limited by the physical characteristics of ultrasound (ultrasound is most afraid of interference from gastrointestinal gas). Even experienced ultrasound doctors, so that there is a high-resolution ultrasound diagnostic instrument, along with the use of gastrointestinal ultrasound imaging fluid to perform gastrointestinal ultrasound examination, can only check the gastrointestinal tract advanced cancer and other obvious lesions; general inflammatory lesions, ulcerative lesions, etc. is unlikely to have characteristic sonographic changes under the ultrasound, and can not be suspected of lesions for pathological tissue biopsy, how to talk about the reason for the diagnosis? At present, the widely used electronic gastroscopy is to extend the gastroscope into the gastrointestinal cavity under direct vision, just like the human eye into the gastrointestinal tract, which can clearly observe the subtle lesions of the mucosa of the gastrointestinal tract (such as minor inflammation, erosion, bleeding, early cancer, etc.), therefore, gastrointestinal endoscopy is recognized as the examination method of choice for patients with gastrointestinal diseases in the world today; it can not only clarify the location, shape and size of lesions under direct vision, but also combine the pathology with the gastrointestinal tract. It can not only clarify the location, shape and size of the lesion under direct vision, but also combine with pathological histological examination to finally get a definite diagnosis. Recently, our gastroscopy department has encountered many cases of patients with chronic gastritis and colitis who were diagnosed with the so-called non-intubated gastroscopy in outside hospitals, but finally all of them were confirmed as intestinal cancer or gastric ulcer by endoscopy and pathology in our hospital. For this reason, we call on all patients not to believe in gastroscopy without intubation, and to go to regular hospitals for gastroscopy for those who have gastrointestinal diseases, so as not to miss the disease and regret too late!