In men with itching in the nipple area, the appearance of the nipple area needs to be carefully observed. If there is no abnormality in the appearance and itching is the main cause, it is possible that the itching is limited and related to allergic irritation. It is recommended to use topical hydrocortisone butyrate cream or Denide cream to effectively relieve itching. If the nipple area appears obvious erythema, papules, or even vesicles, exudation, consider the possibility of nipple eczema, you can choose to glutamate lotion or saline wet compresses, the surface will soon return to dry, and then apply 0.1% tacrolimus ointment or 1% pimecrolimus ointment, with oral cetirizine tablets or ibastine and other antihistamines, can effectively restore the symptoms to normal. Pathological examination should be done for long-term erosion.