The true cure rate for diffuse large B lymphoma is between about 50% and 60%, and the cure rate will be affected by factors such as clinical stage, treatment plan, and your own physical condition. Generally speaking, the true cure rate of diffuse large B lymphoma is about 50%~60%. For people with earlier clinical stage, sensitive to chemotherapy and rituximab, without other underlying diseases or in good physical condition, the cure rate can even reach about 80%. However, for people with later clinical stages, who are not sensitive to the treatment regimen, and who have a combination of underlying diseases, the cure rate is often lower, and may even be less than 50%. When diagnosed with diffuse large B lymphoma, one should go to a regular hospital in time and under the guidance of a doctor for appropriate treatment to improve the cure rate.