Discomfort in the throat is not necessarily a sign of novel coronavirus infection. The portal of invasion of novel coronavirus is the mucous membranes, including the conjunctiva, the mouth, the nose, the pharynx and the respiratory tract, so special vigilance is still required during the epidemic. As the virulence of the virus is diminishing from generation to generation, nucleic acid testing is commonly carried out and many mild cases have been diagnosed. Throat discomfort may be the initial manifestation of some patients with novel coronavirus pneumonia, so subsequent clinical symptoms such as the presence of cough, fever and malaise should be observed. If there are symptoms of cough and fever, one should promptly go to the hospital of the jurisdiction for routine blood tests, lung CT tests and even nucleic acid tests related to the new coronavirus, and appropriate treatment will be given according to the diagnostic criteria for suspected and confirmed cases.