Pain in little toe may be caused by trauma, gout, rheumatoid arthritis, tenosynovitis, corns and other factors. 1. Trauma: If the patient wears ill-fitting shoes for a long time, or suffers from soft tissue contusion due to external collision and other factors, pain in the little toe will occur. 2. Gout: If the patient suffers from gout, when uric acid is deposited in the little toe, it will cause severe pain in the little toe. 3. Rheumatoid arthritis: If the patient has an autoimmune disease, it can cause joint pain in various parts of the body, and pain in the little toe may occur. 4. Tenosynovitis: If the walking time is too long, excessive friction between the tendons and tendon sheaths at the little toe, chronic aseptic inflammatory changes may occur, which may lead to pain. 5. Corns: If the patient’s skin at the little toe is subjected to long-term pressure and friction, causing keratosis. Then corns may occur, which will produce pain. If the patient’s little toe pain pain should go to the hospital in a timely manner to check, clear cause after targeted treatment.