The treatment of sweat rash on the hands includes the following: 1. Oral medication: Oral Orotadine Hydrochloride tablets or Epinastine Hydrochloride capsules can be chosen, if necessary, combined with compound glycyrrhizin capsules to strengthen the anti-allergic, anti-itch, immunomodulatory therapeutic effect. 2. Topical medication: If there are dense small blisters, it is necessary to apply cold wet compresses with decoction of Chinese herbs Huang Lian, Huang Bai, Jin Yin Hua, Lian Qiao, Dan Pi, Sheng Di, Gentian Cao The affected area should be treated twice a day for 20 minutes, and after the compress, Denudation ointment should be applied twice a day. If some of the blisters fuse to form large blisters, sterile acupuncture needles should be used to puncture the wall of the blisters to allow the herpes fluid to escape, reducing local pressure and pain.