Stones in the upper urinary tract may cause stomach discomfort, while stones in the lower urinary tract usually do not cause stomach discomfort. Stones in the upper urinary tract include stones in the upper right ureter and the kidney. Some of the nerves that innervate the kidney and upper ureter have traffic branches with the nerves in the gastrointestinal tract, so if there is a lesion in the kidney or upper ureter, it may cause symptoms of stomach discomfort. This condition is often seen in upper ureteral stones and kidney stones, which present with back pain accompanied by nausea, vomiting or upper abdominal distension and discomfort. If the stone has entered the lower part of the ureter and entered the bladder and urethra, it does not cause stomach discomfort, but only urinary tract irritation such as frequent urination, urinary urgency or flesh-eye hematuria. Therefore, for ureteral stones in the upper part of the ureter, pain relief treatment is needed, as well as treatment to suppress acid secretion, relieve stomach cramps or antiemetic treatment to reduce the symptoms of stomach discomfort. After the stone is discharged into the lower part of the ureter or the bladder, the symptoms of stomach discomfort will be relieved or disappear.