1, why the combination of Chinese and Western medicine We are all very concerned about the topic of the combination of Chinese and Western medicine, Chinese and Western medicine can not be combined? Objectively speaking, it should be able to be partially combined. However, the current situation of the integration of Chinese and Western medicine is not satisfactory, too much form, form is too much content, and the speed of development is quite slow, it is difficult to appear very satisfactory results. I think that there is not enough research on methodology and theoretical foundations for such a situation, which compels us to rethink the bits and pieces of the path taken by the integration of Chinese and Western medicines. After the middle of the 19th century, Western medicine was introduced to China in large quantities. The arrival of missionaries, the translation of Western medical books, the establishment of Western medical schools and hospitals, and the absorption of foreign students all contributed to the overwhelming force of Western medicine squeezing the traditional Chinese medicine. The momentum of Western medicine was so strong and powerful that it almost dominated the central and local health authority, and there was talk of abolishing Chinese medicine during the Republican period. At that time, the petition of the Chinese medicine sector led by Nanjing shocked the whole country, and the four famous doctors in Beijing came into being at this time. Traditional Chinese medicine, with its unique and miraculous curative effects, was able to be preserved in an honorable manner, but it was constantly confronted with the rapid development of Western medicine, which was scorching and pressing. In 1956, Mao Zedong, on the basis that the combination of the universal truths of Marxism-Leninism and the concrete practice of the Chinese Revolution was the magic weapon for the victory of the Chinese Revolution, conceived the idea of creating a new Chinese medicine. He proposed, “Combine the knowledge of Chinese medicine and Chinese herbal medicine with the knowledge of Western medicine and Western drugs to create a unified new medicine and new pharmacology in China.” This is considered to be the original source of the concept of combining Chinese and Western medicine. Earlier, in 1950, at the first National Health Conference held after the founding of New China, the “unity of Chinese and Western medicine” was established as one of the three major guidelines for health work, creating a talisman for the preservation and protection of Chinese medicine. In 1954, Mao Zedong emphasized that “the most important thing in the future is that first of all, Western medicine should learn Chinese medicine, rather than Chinese medicine learning Western medicine.” In this atmosphere, in 1955, the Ministry of Health organized the first nationwide class for Western doctors to leave their jobs to study Chinese medicine (hereinafter referred to as the “Western Study of Chinese Medicine” class). Since then, the country’s systematic organization of “Western learning in” class has continued until about 1976, a variety of off-duty or off-duty “Western learning in” class has just become a medical profession keen to movement. It is undeniable that this period produced a number of excellent specialists in the integration of Chinese and Western medicines. In recent years, the domestic Chinese medicine university set up a combination of Chinese and Western medicine, the purpose is also to strive for more people to do Chinese and Western medicine, grasp the knowledge related to Chinese and Western medicine, but the fact is that the vast majority of doctors have become a simple application of traditional Chinese medicine and Western medicine doctors, saying that what all know a little bit, but when it comes to whether the integration of Chinese and Western medicine can be a blank, it is very difficult to do the integration of real knowledge of Chinese and Western medicine, and also can not be combined with Western and traditional Chinese medicine. Early liberation also pure Chinese medicine to Western medicine learning transformation, Chinese medicine scientifically, so that Chinese medicine to learn the theories of Western natural sciences, such as anatomy, physiology, bacteria, pathology, etc.; Chinese medicine doctors scientifically, that is, by the examination of qualified Chinese medicine practitioners permitted to practise, through the “further training” for the transformation of modern medicine, so that it becomes a “scientific medicine”. “Scientific doctor”. The result is not what we had hoped for! Most of the Chinese medicine “direct replacement of Western medicine”, Chinese medicine hospital leaders are Western medicine, Chinese medicine development direction by Western medicine; and many new graduates of the Chinese medicine college students increasingly westernized, many hospitals, Chinese medicine practitioners even a basic prescription are not complete, but under the guise of Chinese medicine graduates, in fact, basic knowledge of Chinese medicine; many hospitals, Chinese medicine department discussion Many hospitals have no Chinese medicine department to discuss cases; some hospitals have set up Chinese medicine departments for the purpose of grade assessment, and have basically no Chinese medicine thinking and Chinese medicine treatment means. As a result, the combination of Chinese and Western medicine is the westernization of Chinese medicine, and Western medicine is gradually replacing Chinese medicine. In the face of the powerful Western medicine, our Chinese medicine is stubborn, or with the combination of Western medicine is every Chinese medicine people can not avoid the problem, but I think that from the history of the development of Chinese medicine, not only should be combined, and should be combined seriously and well. Chinese medicine is based on the philosophical thinking of the Warring States period before the formation of the historical trend to draw on the scientific knowledge of the time to enrich and improve, as typhoid fever, the formation of the doctrine of warm diseases, the current more should be seriously draw on modern scientific knowledge to enrich and improve their own, in the inheritance of traditional medicine based on the characteristics of the formation of a new Chinese medicine. The combination of Chinese and Western medicine should be one of the mainstream of contemporary Chinese medicine academic thinking, we Chinese medicine must not be stuck in a rut, not from the internal typhoid, to be able to combine the knowledge of the internal typhoid with the knowledge of modern science and carry forward. So it seems that the development of modern medicine is not the existence of traditional medicine extinction road, the combination of Chinese and Western medicine is a stage in the history of the development of Chinese medicine, is the inevitable progress of history, no one can avoid. 2, Chinese and Western medicine really combined? Chinese medicine is “good at poor reasoning, but poor at materialism”, Western medicine “specializes in materialism, but short of poor reasoning”. Chinese medicine focuses on finding the law, macro, Western medicine focuses on intuition, micro, how to combine macro and micro organic complement each other is the way out of the combination of Chinese and Western medicine. The current combination is mostly a simple combination, not in the theory and methodology of organic combination will not produce a real combination. It must be clear: the combination of Chinese and Western medicine (1) is not simply a simple list of Chinese and Western medicines superimposed: such as Zhang Xichun, etc. just choose the advantages of Chinese and Western medicines and can not be a theoretical breakthrough; (2) is not simply the application of the pharmacological knowledge of Chinese medicine to command the use of medicines, at present, many of the West in the study of the Chinese people with the use of this method of medication, less the essence of the traditional Chinese medicine of identification of the treatment; (3) is not simply a Chinese medicine to verify the scientific validity of Chinese medicine, such as Tang Rongchuan and other experimental Chinese medicine. Scientific, such as Tang Rongchuan, etc., which is currently very Changxing, but not much clinical significance, most people in order to report awards, promotion and for, Chinese medicine so that modern medicine is by no means evidence-based medical information and simple combination of disease, Western medicine emphasizes the reductionist and reproducible, acupuncture is recognized abroad is in line with the reductionism of Western medicine and reproducible, acupuncture to do the combination of evidence and disease? Acupuncture in foreign countries is also mainly to solve the pain only, but it can have repeatability, tell him to treat toothache choose Hegu, cheek car, he tied on even if the therapeutic effect is not as good as you, but also can relieve some of the patients with toothache, it is recognized, the West is recognized by the “repeatability”; pain is a disease? Not yet, it is just a symptom. So what should be the real high level of integration of Chinese and Western medicine? I believe that Chinese and Western medicine should be combined on the basis of the correct methodology, a high degree of theoretical integration, can guide the clinical or new therapies, new ideas, or 1 + 1 > 2 efficacy. However, it must be emphasized that the combination of Chinese and Western medicines can only be a partial fusion and mutual understanding, seeking common ground while reserving differences, and it is difficult to completely combine the two theories. The result of the combination of Chinese and Western medicine should be the excavation of Chinese medicine theory, the development of Chinese medicine academic thinking; at the same time for modern medical theory to provide new thinking, clinical provide new methods, evidence-based medicine to improve clinical efficacy. This is the only way to achieve a true combination of Chinese and Western medicine, in order to develop the academic Chinese medicine, but also recognized by modern medicine to learn from the nutrients and so on. 3. How to reasonably combine Chinese and Western medicines to study tumors (1) We must firstly maximize the interoperability of Chinese and Western medicines in terms of disease names. At present, only the names of diseases correspond to each other, that is to say, the combination of a small number of diseases, which is in line with the requirements of the development of modern Chinese medicine, though not perfect. The next step should be to maximize the interoperability of Chinese and Western medical names, the importance of which is self-evident, just like the translation of Chinese and English. In the past, the naming of symptoms in Chinese medicine could not meet the requirements of the current treatment, and could not conform to the direction of the development of the integration of Chinese and Western medicine. For example, we have been engaged in the integration of Chinese and Western medicines for decades, and the first thing we check in blood sampling is blood picture, and the first one in blood picture is white blood cell, so what is white blood cell? There is no corresponding concept in Chinese medicine before us, but I think it is Weiyang, and the white blood cell can be raised rapidly by supplementing Weiyang, which proves that the corresponding concept we determined is correct, and the specific reason why the white blood cell and Weiyang are interoperable is referred to the “Golden Chang Oncology”. The 20 Years of Experience in Myelosuppression Diagnosis and Treatment” for 5 reasons. Previously, Wei Yang and Ying Yin were talked about together in Chinese medicine, and it was rare to talk about treating diseases by regulating Wei Yang alone. The correspondence between hanging drinks and pleural fluid: Chinese medicine does not have the concept of pleural fluid because there is no imaging in Chinese medicine, but there are hanging drinks in Chinese medicine, and the symptoms of hanging drinks are similar to those of pleural fluid, so the two can be corresponded to each other. In traditional Chinese medicine, drinking is mostly caused by yang deficiency, so it is necessary to warm yang to promote water, so the treatment of pleural fluid has the effect of warming yang of western medicine interleukin-2, and warm yang anticancer topical creams and warm needle therapy, which have achieved significant clinical results. It can be seen that due to the correspondence between pleural fluid and hanging drink, that is to say, it can clarify the reason why interleukin-2 is better in treating pleural fluid, and it also provides ideas for the treatment of pleural fluid in Chinese medicine. The maximum interoperability of Chinese and Western medicine names can provide great convenience for scientific research; but also for the screening of Western medicine effective treatment means to provide the basis for exploring Chinese medicine treatment of modern diseases to provide ideas. (2) must maximize the mastery of the theoretical knowledge of Chinese and Western medicine To achieve the combination of Chinese and Western medicine must maximize the mastery of the theoretical knowledge of Chinese and Western medicine, carefully analyze the similarities and differences, it is possible to achieve the integration of Chinese and Western medicine, put forward new theories, new ideas, resulting in a 1 + 1 > 2 effect of treatment. The following is the entry point for me to look at the problem and generate new ideas for your reference: First, we will look at the promotion of white blood cells: as mentioned above, white blood cells correspond to the Wei Yang of Chinese medicine, and the promotion of white blood cells in western medicine relies on the white blood injection, which has a short-lived therapeutic effect and promotes the metastasis of the tumor. So can we not promote white from the perspective of Wei Yang? Wei Yang out of the lower jiao, relying on the good offices of the spleen and stomach in the state of the dissemination of the whole body, from which I thought of moxibustion Guanyuan, in the middle of the epigastric region, Shenque, foot Sanli to achieve the purpose of ascending the white, and not surprisingly, often 3 days after the white blood cells rose to normal. Look at how to transfer granulocytes to the peripheral blood: doctors of traditional Chinese medicine say that the use of traditional Chinese medicine or traditional Chinese medicine methods can promote white, but we can transfer granulocytes from the bone marrow to the periphery? I think we may not even think about it. We often say that the western medicine white needle is to transfer the granulocytes from the bone marrow to the periphery, then we Chinese medicine whether there is a way to transfer the granulocytes? “Only can’t think, no can’t do”, this is the slogan of our Huangjiajun team, we believe that the white blood cells are with important defense function, it can be divided into granulocytes and non-granulocytes. Granulocytes play a very important role in the non-specific cellular immune system, while granulocytes mainly play a specific immune role. Externalizing granulocytes is nothing but mobilizing the body’s non-specific immune function and enhancing the immunity of the whole body. If we artificially create a foreign body as large as possible in a patient, is it possible to mobilize granulocytes to phagocytose the foreign body. We chose to scrape on the sun bladder meridian, which has the widest circulation in the human body, and the next day we checked the blood of the patients, and the result was that more than 90% of the patients’ granulocytes were improved, and the highest one was more than 120%. This can improve the immune function, but also can be very good to the granulocytes to the periphery of the simple and practical Gua Sha therapy can not be said to be the model of the combination of Chinese and Western medicine. Local targeting immunity tumor suppression said: western medicine first proposed with biological therapy, whole body immunity, first popular in Japan, life is very short; spread to Taiwan, also did not see a rise; spread to the Chinese mainland but carried out in full swing ……. Tumor is a foreign body, first release PDL-1, so that T cells programmed to die, not recognized by the surrounding immune cells. How to get the immune system to recognize it, attack it, and then destroy it involves the concept of local immunity. Localized immunity, can TCM do it? Of course it can. This is the tumor local acupuncture, acupuncture artificially created a foreign body, greatly stimulate the local immune function, immune cells will go to the siege to destroy the tumor, this is what I put forward “local targeted immunity tumor suppression” initial thinking. If we do not understand Western medicine and the concept of Chinese medicine is not very clear, it is impossible for us to put forward these new theories and methods that are conclusive and effective. Chinese medicine people should be quiet to read the classics, the language is difficult to understand is by no means the reason we do not accept; the ancients often do not write a clear narrative, often only put forward the two ends of a thing, that is, what and how to do, the middle of the rationale is not put forward, read the classics, we have to read out the “way” to be able to integrate. (3) must pay attention to the methodology of the cognitive research “concept determines the method, the method determines the result”, this is the unchanging truth, to truly integrate Chinese and Western medicine must also be from the methodology of the work. ① from the macro and Western medicine micro combination of Chinese medicine, is a strong combination Sprained after the swelling: Western medicine first cold compresses, hot compresses, cold compresses so that the vasoconstriction, oozing fluid to reduce the swelling and pain will be reduced, hot compresses so that the stasis of the site of the dredging; but first cold compresses after the hot compresses will generally produce sequelae, that is, the folk said that rheumatism pain, Western medicine according to the sprain pathology from the vasoconstriction and relaxation of blood vessels to the treatment of micro-understanding. Chinese medicine, I directly with moxibustion, the first warm through the blockage, both swelling, but also to avoid sequelae, Chinese medicine is to look at the external manifestations of sprains and take the therapy, Chinese medicine can not see the inner blood vessel form, that “blood is not good for water”, edema is caused by blood stasis, treatment with moxa warm through the blood naturally edema disappeared, this is the macro-understanding! This is a macroscopic understanding. If in the game field western medicine treatment can quickly reduce the pain to resume the game, but in other cases with direct moxibustion can be, will not leave sequelae. If the combination of cold compresses and moxibustion, moxibustion is much stronger than hot compresses, and will not leave sequelae, this is the application of strong combination. Targeted drug therapy of Western medicine target and Chinese medicine macro-identification: Western medicine is often based on the results of genetic testing of tumors to choose targeted drugs, even if the test results are fully consistent with the efficiency is 70% -80%, then in addition to the gene there are factors affecting the efficacy of the drug, in the end, which genetic factors affect the efficacy of the drug is not yet clear, which is the microscopic understanding of the modern medical science. We have had a macroscopic understanding of the Chinese medicine identification and site identification of the drugs such as Eraser and Trocar, and we believe that the indications of Trocar and Eraser are the patients with lung adenocarcinoma with cold and dampness, with peripheral foci, and mostly combined with pleural fluid and pericardial effusion, etc. The gene mutation is related to the location of the tumor, which is the same as the gene mutation. Is there a relationship between gene mutation and the location of the tumor? I once asked my student Tian Zhen to organize the relationship between the location of lung cancer and the effectiveness of targeted drugs, and found that there is a close connection between them. Well, if we can identify the indications for targeted drugs in Chinese medicine, even if we don’t check for EGFR in the clinic, we can still select targeted drugs effectively based on where the tumor is located and what the Chinese medicine identification is. If we can combine Chinese medicine identification and target detection, the efficiency of targeted drugs will be greatly improved, which is also an example of strong combination. ② Must focus on complementarity Ⅰ. Multi-targeting of Chinese medicine and Western medicine combined with a single target: multi-targeting of Chinese medicine, including a drug multi-targeting and drug combination of multi-targeting, a drug can have multiple effects, a method of multiple roles, which is precisely the advantages of Chinese medicine. This is precisely the advantage of TCM. Western medicine is mostly single-target. If the two can be effectively combined, they can complement each other. II. Complementary advantages: Chinese and Western medicine have their own advantages, and if we utilize their advantages to help each other, the curative effect will be improved naturally. For example, I propose that “tumor is a xenobiotic organism in which the autologous cells in the region mutate and proliferate without being recognized and inhibited by the surrounding immune cells after the local internal environment is changed”, which includes three meanings, one is the soil theory of Western medicine, i.e. “internal environment”, the other is local immunity, and the other is tumor. One is the soil theory of western medicine, i.e. “internal environment”, the other is local immunity, and the other is tumor, which is a complete expression of the cause of tumor formation. For these three aspects, western medicine is stronger than anti-cancer, almost all the treatments in western medicine mainly target xenobiotics-“tumor”, which is the strong point of modern medicine, but anti-cancer cannot solve the recurrence and metastasis of tumor well. Chinese medicine has advantages in improving the internal environment and changing the soil; acupuncture has advantages in improving the local immune function; the internal environment and local immunity are the most important factors for tumor recurrence and metastasis, which is the strong point of Chinese medicine. If Chinese medicine can change the internal environment, acupuncture to improve the local immune function, and western medicine to suppress the tumor, it will undoubtedly solve all the problems of tumor growth, recurrence and metastasis. 4.Tumor combination of Chinese and western medicine ideas and practice The following introduces a few angles of our combination of Chinese and western medicine for your reference, as if to throw a brick to attract jade. (1) Make full use of the anatomy of acupoints to use needles We should make good use of the anatomy of acupoints to guide the use of needles, which is the basis of our use of needles. Although the essence of the meridians is still a mystery, but from the anatomy of the acupuncture points, can help us think about the role of acupuncture points from multiple perspectives, as well as to guide acupuncture and understand the contraindications of acupuncture. You can refer to books such as Anatomy of Acupuncture Points by Prof. Yan Zhenguo. Let’s give a few examples for your perceptual understanding. ① clever use of acupuncture points and the relationship between the surrounding organs: for example, common pharyngitis, we all know that pharyngitis can be seen in the posterior pharyngeal wall follicle formation, capillary disorders, localized edema, for pharyngitis Chinese medicine on the use of acupuncture tianchu acupuncture point, and we believe that the treatment of pharyngitis should be to stimulate the localization of the posterior pharyngeal wall to improve the edema, according to the anatomy of the acupuncture points, tianrong acupuncture point, lianquan acupoints located in the vicinity of the throat, acupuncture tianrong acupoints to the posterior pharyngeal wall into the needle Direct effect on the local, and then with the Lianquan to the posterior wall of the pharynx into the needle also stimulate the local treatment of pharyngitis, the effect is like a beam; and by extension, the pharynx near the disease, such as radiation therapy after the sore throat, dry mouth, tonsil tumors, etc., can be taken to the Tianrong, Lianquan acupoints. Ancient people have many taboos on the day of acupuncture acupuncture point, do not dare to enter the needle, even if the needle is shallow, for fear of life-threatening. Is the fact so terrible? Through the anatomy of the points, as long as you master the correct technique, the needle is even deeper will not be a problem. Moreover, even if the needle is stuck on the blood vessels, there will not be a lot of bleeding, and there will be a fluctuating sensation when the needle is stuck on the blood vessels, so it is better to avoid it. This is the wisdom we gain by fully utilizing the anatomy of acupuncture points. ②. Skillful use of anatomical sites needling: “stomach around the periphery of the stabbing seconds to kill loss of appetite”, we once treated a loss of appetite of lung cancer patients, the usual very useful methods have been exhausted, the patient is still reluctant to eat. What to do? The stomach is not moving, how to make it move? That is along the stomach around the mannequin prick, into the needle after the stomach as long as the eyes to avoid the new mannequin, to avoid the need to peristalsis, the stomach will be peristalsis will be emptied will appear hungry, appetite. I let the students in the patient’s stomach around the prick, less than 1 minute, the patient asked for food, the effect of the fast, we describe it as “seconds”. ③ skillfully use the back of the Yu point and its nearby nerve relationship to treat diseases related to viscera: bladder meridian back Yu point corresponding to viscera on the application of the back of the acupoint provides great convenience. Modern research has confirmed that the location of the dorsal acupoint is adjacent to the root of the spinal nerve, sending out various spinal ganglia of the spinal nerve, sending out the nerves innervating the sympathetic and parasympathetic nerves of the thoracic and abdominal cavity viscera, and certain parts of the trunk nerves. Stimulation of dorsal acupoints can treat the corresponding viscera or body surface diseases through nerve conduction. Clinically, we use blood cupping and fire acupuncture to treat related diseases such as asthma, coronary heart disease, intestinal obstruction, constipation, gastric paralysis, etc., with remarkable results. A colon cancer lung metastasis patients, chest CT on the lungs have almost not see through the place, we describe the “big white lungs”, the patient wheezing, can not lie down all day long, and sometimes even have a sense of imminent death, the student Jiang Xin in his back lung Yu, fixed wheezing points such as gua sha, blood cupping, wheezing to meet the solution, the patient was discharged from the hospital, like the There are many examples like this. Students Zhao Weipeng to a patient with intestinal obstruction in the corresponding dorsal Yu points on the blood cupping, less than 2 minutes, the patient ventilated, the speed of the fast, students and patients are unexpected. (2) Pathophysiology to guide the identification of Chinese medicine Our graduating students have studied pathophysiology, we may not think we can skillfully use pathophysiology to guide the identification of Chinese medicine. ①Use of vascular wall plaque formation and lipid deposition related to the inhibition of blood vessel formation by resolving phlegm to pass through the blood vessels: people who have studied cardiovascular pathophysiology know that the formation of vascular wall plaque is related to lipid deposition of blood vessel wall, damage to the endothelium of the blood vessels, but who would have thought that it can be used to inhibit the formation of blood vessels by resolving phlegm to pass through the blood vessels. We like to apply ten jujube soup to treat tumors related to phlegm, after applying for a period of time, ultrasound found that some patients’ tumors did not shrink but the blood flow in the tumors disappeared, which precisely provides ideas for the inhibition of angiogenesis research and development. Inhibition of angiogenesis does not have to focus only on blood vessels, can start from the inhibition of plaque formation, Chinese medicine said that the phlegm turbid through the collaterals and veins method can inhibit angiogenesis. It also shows that phlegm and stasis are important tumor pathologies. Cyclic change of endometrial thickening and blood stasis in endometrial cancer The endometrium will change cyclically with menstruation, and when the endometrium is thickest is when blood stasis is heavy before menstruation, and once menstruation comes, the endometrium will become thinner when the blood stasis is gone. Thus, it can be seen that blood stasis exists in endometrial cancer (endometrial thickening). Clinically, triamcinolone acetonide tends to cause endometrial cancer. What conditions and what factors go downward to cause endometrial cancer? When Cold tends to go downward and congeal in the uterus, Blood stasis becomes present. Therefore, it can be concluded that triamcinolone acetonide is a cold medicine, and endometrial cancer is caused by cold condensation and blood stasis. The theory of the sages more than 2000 years ago confirms that our present speculation is correct, for the “stone obstruction” in the abdomen is caused by cold condensation in the uterus. (3) Use pathology to identify small cell lung cancer and squamous carcinoma with phlegm factor. From the point of view of pathological forms, small cell lung cancer is granular and dense, squamous carcinoma is streak-like and scattered. Comparing to nature, those favoring cold like to gather in groups and those favoring heat are dispersed and arranged, then it can be said that squamous carcinoma is more fire than phlegm, and small cell carcinoma is more phlegm than phlegm. The nodule formed by pancreatic cancer is raised on the surface of pancreas, which is analogous to the hard lumps in life, indicating that pancreatic cancer is definitely heavy in external cold, and there is also internal heat with phlegm and stasis. (4) According to the location of imaging tumor to help TCM identification Firstly, look at lung cancer, no matter small cell carcinoma or squamous cell carcinoma by the lung door, all of them are related to smoking, so they are partial fire; located in the periphery of partial cold. The scattered nodules in the lungs are related to emotions and feelings, how did I analyze and speculate? We look at the CT film of thyroid cancer lung metastasis, is scattered cotton wool-like clumps, I accordingly introduced, scattered foci in the lungs of the patient more related to the mood, clinical confirmation of my point of view, this kind of patient temper can not be small, very character, with the characteristics of the liver wind. By extension, herpes zoster, like beads, rapid development, with the characteristics of the wind; irritating cough, paroxysmal, also with the characteristics of the wind, with Dai Clam San. Then look at the abdominal wall metastatic tumor: those tumors are easy to abdominal wall metastasis? Ovarian cancer is common, as well as bile duct cancer. Some of the abdominal wall metastatic tumors are similar to the manifestation of acute peritonitis. With the idea of treating acute peritonitis, treating peritoneal metastatic carcinoma with Da Trap Thorax Soup, the effect is remarkable, and it can be speculated that peritoneal metastatic carcinoma is inclined to phlegm-fire. It can also be speculated that tumors that are easy to cause peritoneal metastasis contain phlegm-fire, in fact, ovarian cancer and cholangiocarcinoma have phlegm-fire factors. (5) Relationship between site, pathology and yin and yang The site here is different from imaging, which refers to the part that can be seen by naked eyes. According to Chinese medicine, “clear yang hair coupling, turbid yin goes to the five viscera” and “up is yang, down is yin”, it is not difficult to find out that tumors that are connected with the outside world, near the body surface, head and neck, and thoracic cavity belong to fiery and hot tumors, and the pathology of squamous carcinoma and small-cell carcinoma is more common; and in contrast to that, tumors that are located in the inner, lower, and abdominal cavity often have phlegm and fire factors. In contrast, tumors located in the inner, lower, abdominal and pelvic cavities are mostly cold, and adenocarcinomas, mucinous and plasma tumors are more common. Take digestive tract tumors as an example, tumors of oral cavity, pharynx and esophagus are often squamous carcinomas, while those below cardia until sigmoid colon become adenocarcinomas, and tumors in anal canal become squamous carcinomas. Adenocarcinoma of the endometrium is common, and the cervix is connected with the outside world and becomes squamous carcinoma. Some parts of the body are not necessarily related to pathology, but I still categorize them according to TCM theory. For example, I artificially categorize pancreatic cancer into pancreatic head cancer and pancreatic body tail cancer; pancreatic head cancer is prone to yang-huang and is hot in nature, while pancreatic body tail cancer is more painful and cold in nature, encircling the large blood vessels. I have always been dissatisfied with the classification of lung cancer in modern medicine, which is unscientific to categorize lung cancer into small cell lung cancer and non-small cell lung cancer, and adenocarcinoma and squamous carcinoma are categorized as non-small cell. Personally, I believe that the correct classification is either to separate all three, or to group squamous carcinoma with small cell carcinoma. For tumors of various parts of the whole body and the pathological evolution law, see the book “Ten lectures on tumor identification and treatment in Chinese medicine by Jin Chang”. (6) Classify chemotherapeutic drugs and targeted drugs according to their side effects to improve their efficacy I have discussed this in detail in this book and the book “Ten Lectures on TCM Tumor Recognition and Treatment of Jin Chang”, so I will not elaborate on it here. (7) To guide the use of drugs according to the side effects of drugs Clinically, fever would occur when using large amounts of interleukin-2 (IL-2), but it is not easy to determine whether the properties of the drug are cold or hot, because the pathogenesis of fever can be either cold or hot. Later, when IL-2 was given in large doses intravenously, skin flushing occurred due to increased capillary permeability, and at this time it could be determined that it was a hot drug. And pleural fluid, as the internal scripture said, “all diseases, water and liquid, clear and cold, all belong to the cold”, thus the idea of injecting IL-2 into the chest cavity for the treatment of pleural fluid, the effect is really better than other drugs. (8) The concepts of Chinese and Western medicine converge to explore the treatment method, which has already been discussed in this article. (9) Correspondence between clinical manifestations and Chinese medicine concepts to find treatment ideas Extra-organ lymphoma and other tumors correspond to meridian lesions: few lymphomas grow on organs, but many grow outside of organs, and those outside of organs correspond to meridians in Chinese medicine, and extra-organ lymphoma corresponds to meridian tumors. Tumors in meridians also have the characteristics of deficiency, phlegm, blood stasis and toxicity, which drugs can make up for the deficiency of yin and yang, qi and blood in meridians; which drugs can remove phlegm and blood stasis in meridians; which drugs can remove cancerous toxins in meridians, such as these are clear, we can treat lymphoma in meridians and other malignant tumors in meridians, we should not focus on cancerous tumors of internal organs and neglect cancerous tumors of meridians, in fact, meridian cancerous tumors also have a lot of them, go back! In fact, there are quite a number of meridian cancer tumors. You should go back and search for drugs related to the treatment of meridian lesions, and I will talk to you again when there is a chance. Nerve tumors also have the characteristics of neuropathy: deficiency wind, phlegm, stasis and Yang deficiency. In nerve diseases, the symptoms mostly include trembling, which is characterized by deficiency wind; numbness and woodiness, which is related to phlegm and stasis; nerves are like the guide wires in electric wires, which are pure yang, and when there are lesions in nerves, there exists the aspect of yang deficiency. Red blood cells, platelets do not correspond to the concept of Chinese medicine, which is not difficult for us, we can be from the function of red blood cells, platelets to explore the ideas of traditional Chinese medicine treatment: red blood cells is the concept of Western medicine, which is lower than the normal value is anaemia, anaemia does not correspond to the Chinese medicine of the blood deficiency, if you take the anemia corresponds to the Chinese medicine of the blood deficiency to treat the effect is not ideal. Red blood cells are the ying yin in the vein, carrying oxygen, long life, it is not difficult to think of ying yin from the spleen, stomach, lungs, exchange of oxygen, yin is difficult to quickly with the spleen and kidney of the yin, so I often use the self-prepared Jin Gui Tuan Yuan Fang to tonify the kidneys, strengthen the spleen and benefit the lungs to elevate the red blood cells, the formula to raise the effect of blood pigmentation is quite fast, quite good. Platelets are easy to aggregate, with coagulation function, from the theory of traditional Chinese medicine and coagulation related organs including liver and spleen, liver blood, spleen blood, so we can regulate the liver and spleen in order to ascending platelets, regulating the liver and spleen can be selected in the back of the liver yu, spleen, diaphragm, etc., blood cupping, but also in traditional Chinese medicine to choose to nourish the blood, replenish the blood and cool the blood, replenishment of blood and qi in order to regulate the liver and spleen, cool the blood in order to prevent bleeding. (10) Chinese medicine theory to explain the confusion of Western medicine, for Western medicine to help Explanation of irinotecan dosage difference: irinotecan in small-cell lung cancer dose is small, and ovarian intestinal tumors dose is large, why is this so? Pfizer says it’s an evidence-based result that Western medicine can’t say. My explanation is that irinotecan is a hot and dry drug, and both heat and dryness remove dampness. Dampness tends to go down, the further down the dampness, the heavier, need to remove the dampness of irinotecan accordingly the larger the dose. Cough with sparse phlegm: Western medicine treats coughs by either stopping the cough strongly or promoting the cilia to oscillate and expel phlegm, but not going to the root. Chinese medicine, the spleen and stomach for the source of phlegm, the lungs for the storage of phlegm, with the method of treating the spleen and stomach, simple two medicines, ginger and jujube boiled water to drink, not only treat the spleen, but also treat the stomach, is to treat the root of the method, although not to treat phlegm, but the cough sparse phlegm naturally disappeared. This provides ideas for Western medicine to cure phlegm cough. Laxative problem: Western medicine also recognizes the promotion of intestinal power to defecate, but the corresponding drug cisapride because of problems and stop using. What does TCM do? Use raw atractylodes to promote intestinal motility so that stools are naturally easy to pass. To strengthen the re-understanding of disodium pamidophosphate to reduce organ metastasis: I said in the book “Jin Chang Chinese medicine tumor identification and treatment of ten lectures” that disodium pamidophosphate is a cool medicine, it is a blood-activating medicine, why? Bone metastasis patients appear bone pain, with antipyretic analgesic drugs effective, morphine class instead of the effect is not good, because the former is cool, the latter is hot. Breast cancer is hot cancer, bone metastasis with osteolytic destruction is common; lung cancer pathology is diverse, there are hot squamous carcinoma, small cell carcinoma, there are cold adenocarcinoma, its bone metastasis can be seen both osteolytic destruction, can also be seen osteogenic destruction. Therefore, disodium pamiphosphate has the highest effective rate in treating bone metastasis of breast cancer, followed by bone metastasis of lung cancer. Since disodium pamidophosphate clears heat and activates blood circulation, it can reduce the chance of organ metastasis, which is also confirmed by modern medical science, and the combination of disodium pamidophosphate with chemotherapy is likely to improve the efficacy of chemotherapy for tumors closely related to blood stasis, such as esophageal cancer, gastric cancer, gynecological tumors, and so on. (11) Expand the imagination space, the convergence of Chinese and Western medicine We may think that this sentence is empty, in fact, not, sometimes found that two seemingly unrelated issues are in fact closely linked, which needs to be built between a bridge to connect, the establishment of this bridge requires a lot of knowledge related to Chinese and Western medicine. Such as gua sha therapy will granulocytes to the periphery; reconstruction of the tumor area targeting immunotherapy doctrine, etc., there are many such examples, such as vitamin C lower transaminase and liver method: now the treatment of the liver, more obsessed with “see the liver disease, know that the liver spreads to the spleen, when the first solid spleen,” as a matter of fact, purely complement the spleen to cure the liver effect is not ideal. I don’t know, the original text also has: “If the disease of the liver, tonic with acid, help with the bitter Jiao”. I treat liver and gallbladder disease, with acid medicine, such as ume, white peony, cornelian cherry meat is more, the treatment of liver disease effect is satisfactory. Once, one of our patients aminotransferase is very high, please infectious disease consultation, consultation advice is 100 ml of saline with 3 grams of vitamin C, with the aminotransferase down, vitamin C is very acid, which is in line with Chinese medicine to treat the liver with acid reasoning. Now the extract of Schisandra chinensis biphenyl dibenzoate for the treatment of elevated aminotransferases, take the effect very quickly, but also precisely the use of Schisandra chinensis acid flavor. “If the liver is sick, tonify with acid” is the way to treat the liver. Thoughts on malignant effusions: Cerebral effusion and ascites are similar in that both are organs and tissues in water, unlike pleural effusion and pericardial effusion, which are isolated water. I thought to myself, if the water from the thoracic cavity runs into the abdominal cavity, is the effusion that forms still diffuse ascites? It shouldn’t be, it should be isolated water such as perihepatic fluid and perisplenic fluid. Why is that? No one ever mentions this. Different modes of existence of the same effusion must suggest different pathologies. How to think about isolated water and diffuse water? In my opinion, isolated water is the evil of drinking, which is caused by Yang Qi not being transformed; diffuse water is the evil of dampness, which is caused by Spleen Dampness not being transported, and the treatments are certainly different.