It is not recommended to drink alcohol while taking cold medicines. If you want to drink alcohol, you should drink it after you have recovered from a cold and stopped taking the medicine for 3 days. Drinking alcohol after taking cold medicines during a cold is not only detrimental to the efficacy of the medicine, but may also produce adverse reactions, which are not favorable to the recovery of the cold. Cold medicines may include non-steroidal anti-inflammatory drugs (NSAIDs), which are irritating to the gastric mucous membrane, and alcohol also stimulates the gastric mucous membrane, so drinking alcohol after taking cold medicines may cause adverse reactions in the stomach. In addition, the metabolism of non-steroidal anti-inflammatory drugs will produce toxic substances, which need to be combined with glutathione to reduce the toxicity, while alcohol consumption will consume a large amount of glutathione, which may lead to an increase in the liver and kidney toxicity of the drug. If you are taking cephalosporins, you should not drink alcohol. Cephalosporins can cause the metabolite of alcohol, acetaldehyde, to be unable to be degraded, which in turn can cause acetaldehyde toxicity. Cold and flu is recommended to consult a doctor in a timely manner, under the guidance of a professional doctor, and during the cold and flu need to rest, drink more water, avoid alcohol and tobacco, pay attention to keep warm.