After sodium vitaminate injection, some patients may develop rash, itchy skin, red fever, nausea, vomiting, or shock in severe cases. If rash symptoms appear, you can temporarily do not need to treat, after stopping the drug will slowly recover, regular review in the hospital can be. For people with allergies, liver function abnormalities, or local infections, the drug must be used with caution and care, and strict aseptic operation must be observed during the injection process to prevent local infections. If the fluid in the joint cavity is large and needs to be extracted by puncture, it is usually because the patient has an allergic reaction, so an allergy test must be done before using the drug, and ensure that the injection is done in a sterile manner.