The enema should be controlled by the temperature, concentration, flow rate and pressure of the enema solution and the amount of liquid. In the case of typhoid patients, the enema solution should not exceed 500 ml, the pressure should be low, that is, the liquid surface and the anus should not exceed 30 cm, and the cooling enema should be kept for 30-40 minutes before discharge, and the body temperature should be tested 30 minutes after defecation. Observe the patient’s reaction during the enema, if there is pallor, cold sweat, severe abdominal pain, rapid pulse, panic and shortness of breath, stop immediately, observe and monitor changes in vital signs in a timely manner, and if necessary, may also need to maintain the stability of vital signs with fluids. There are contraindications to enemas, and its main contraindications are acute abdomen, gastrointestinal bleeding, pregnancy, and severe cardiovascular disease.