The management of high uric acid should be based on the cause and condition of the patient and the corresponding treatment methods to lower uric acid, but also in combination with daily general conditioning, so as to achieve better results. For hyperuricemia and gout, which are often accompanied by metabolic syndrome, comprehensive treatment such as hypotension, lipid reduction, weight loss and improvement of insulin resistance should be actively carried out. The saturation and concentration of uric acid in the body at 37℃ is about 420μmol/L (7mg/dl), and over this concentration is hyperuricemia. Clinically, it is divided into primary hyperuricemia and secondary hyperuricemia, and long-term hyperuricemia may lead to gout, so its management includes the following aspects. Primary hyperuricemia and gout lowering uric acid conditioning include: 1, general treatment: control total dietary calories; limit alcohol consumption can high purine food intake; drink a lot of water to increase uric acid excretion; careful use of drugs that inhibit uric acid excretion such as thiazide diuretics; avoid triggering factors and actively treat related diseases. 2.Treatment of hyperuricemia: The aim is to maintain the normal level of uric acid. Mainly include: uric acid excreting drugs such as benzbromarone, drugs to inhibit uric acid production such as allopurinol, alkaline drugs such as sodium bicarbonate, new uric acid lowering drugs such as selective uric acid reabsorption inhibitors. 3.Treatment of acute gouty arthritis period: Colchicine, non-steroidal anti-inflammatory drugs and glucocorticoids are the first-line drugs for the treatment of acute gouty arthritis and should be used early. 4. Treatment of intermittent and chronic gout attacks: For patients with frequent attacks of acute gouty arthritis, chronic gouty arthritis or gout stones, uric acid-lowering therapy should be performed. For, the management of secondary hyperuricemia: actively treat the primary disease; try to avoid or reduce the use of drugs and methods that may trigger and/or aggravate hyperuricemia; control the acute gouty arthritis attack as soon as possible. Therefore, the management of high uric acid is not single, but needs to be integrated with the condition under the guidance of clinicians.