It is not normal for the drain opening to keep oozing after abdominal surgery. Considering the infection, it is necessary to improve the culture of secretion and give anti-infection treatment. It is normal to have some oozing from the drain opening 1~2 days after abdominal surgery, but it is abnormal to keep oozing, and it is necessary to consider the possibility of secondary infection of the drain opening, which must be strengthened with dressing change treatment, and the aseptic operation must be strictly adhered to in changing the dressing, so as to avoid re-infection. The patient’s wound secretions need to be retained for bacterial culture and drug sensitivity test, first broad-spectrum anti-infection treatment, such as giving cefprozil tablets or intravenous levofloxacin injection, etc., and wait for the results of the culture to come out to choose the appropriate drugs. During this period, the patient’s condition must be closely monitored, mainly including temperature, heart rate, blood pressure and other vital signs, and if necessary, blood routine and other laboratory tests, according to the actual situation of the patient to give appropriate treatment. Abdominal surgery after the drain mouth has been oozing should be timely medical treatment, under the guidance of a professional doctor standardized treatment, so as not to delay the condition.