Wound pain after radiotherapy may be a wound healing problem or an adverse reaction caused by radiotherapy, which can be treated with anti-infection, surgical treatment, reducing tissue edema and pain relief as prescribed by the doctor. Poor wound healing can lead to local redness, swelling, pain and other symptoms of infection can be applied antibiotics, such as levofloxacin, azithromycin, etc.; if the wound scar hyperplasia, etc., but also need to carry out conventional surgical treatment. If wound pain with redness, swelling, blisters, broken skin, etc. occurs after radiotherapy, it is often caused by radiotherapy. The most common is the skin and mucous membrane damage, after the end of radiotherapy application of hormonal drugs to reduce tissue edema, with the repair of mucous membrane, the pain will eventually disappear, in addition to painkillers can be used to improve. Regular review after radiotherapy, during radiotherapy need to keep the irradiated skin dry, hygiene, patients should also pay attention to light nutritional diet, sleep and rest, the wound pain after radiotherapy need to consult a doctor in a timely manner, to clarify the cause of the disease and then do further treatment, do not unauthorized use of medication. Please strictly follow the doctor’s instructions, do not self-medication.