Migraine is a vascular neurological disorder that can have a serious impact on the patient’s life and work. Migraines are usually characterized by throbbing pain or dull pain in one or both sides of the head and face, commonly around the auriculotemporal temples, around the orbits and in the posterior occipital region. Migraines can be mild or severe, and many patients with intractable migraines tend to be very severe, with severe pain and frequent attacks, often accompanied by fear of light and noise, nausea and vomiting. When many patients get sick, the first thing they think about is what kind of medicine is good for migraine. But in fact, this idea is too limited and sometimes even misunderstood. If the migraine is mild, then you can take medication to relieve it, but if it is a persistent migraine, taking medication is often ineffective and can produce many side effects. In reality, there are many patients with intractable migraine who have been taking various pain medications for a long time, which have caused serious damage to their body functions, damaged their digestive system, damaged their liver and kidney functions, and drastically reduced their body immunity. Therefore, migraine may not necessarily have to be treated with medication, and further treatment measures should be considered in a timely manner for intractable migraine to carry out effective treatment and get rid of the dilemma of taking medication for a long time. At present, surgery is a good choice for the treatment of intractable migraine, among which microvascular decompression can treat intractable migraine. Microvascular decompression is a very safe and minimally invasive procedure that can reach the lesion and eliminate the root cause of pain, thus achieving satisfactory results.