Although “atrial fibrillation” is an important part of health science, it has been repeatedly taught in our previous content. However, in actual clinical practice, we still encounter many patients who do not take AF seriously, resulting in irreversible consequences, which is very heartbreaking. The prevalence of atrial fibrillation in people over 70 years of age is more than 5%, and the incidence of thromboembolism due to atrial fibrillation is 3%-8%, of which the clinical risk of stroke is the greatest, with stroke causing disability in mild cases and in severe cases, seriously affecting the quality of life. The incidence of stroke due to atrial fibrillation is also increasing with age, and the incidence of stroke due to atrial fibrillation is 4 or 5 times higher in the elderly population aged 80-89 years than in other age groups with atrial fibrillation. The incidence of stroke is greatly increased when combined with a history of embolism, hypertensive disease, diabetes, coronary heart disease and other diseases. So how do we reduce the occurrence of stroke in atrial fibrillation? 1, first of all, we must treat atrial fibrillation with the right attitude. Do not take “atrial fibrillation” to heart, must discuss with professional doctors, according to their own health conditions to take certain treatment measures. 2. “Early elimination of atrial fibrillation reduces the risk of stroke”. Studies have shown that converting atrial fibrillation to a normal rhythm (i.e., resetting) can effectively reduce the incidence of stroke. The main treatment options are traditional conservative medications, surgical procedures, and catheter-based radiofrequency ablation, which is a minimally invasive interventional technique. Compared with the first two treatment methods, radiofrequency ablation has the advantages of being minimally invasive and having fewer side effects, and is now widely used in the treatment of atrial fibrillation resuscitation. For patients with catheter ablation indications, it must be said that atrial fibrillation ablation is an excellent choice. 3, anticoagulation is particularly important. Anticoagulation is a necessary route to reduce stroke in patients with atrial fibrillation, especially in patients with permanent atrial fibrillation. Currently, oral anticoagulants mainly include traditional warfarin, as well as new oral anticoagulants such as dabigatranate and rivaroxaban. Warfarin is still the “mainstay” of anticoagulation in clinical practice. Warfarin anticoagulation reduces the risk of stroke by 68%, but it is important to note that warfarin should be taken regularly under the guidance of a physician and that coagulation should be monitored regularly. (See previous section “Warfarin Precautions”). You can also use new anticoagulant drugs that have been marketed in recent years, such as dabigatranate capsules, etc. Its biggest advantage is that it does not require regular monitoring of coagulation function, but, of course, the cost is relatively more expensive. 4, can not tolerate anticoagulation treatment, can choose “left ear blocking”. Research shows that 90% of the blood clots formed in atrial fibrillation originate from the left heart ear. The “left auricular occlusion” can effectively isolate the left auricular cavity from the left atrium, thus reducing the formation of thrombus. After “left auricular occlusion”, only a period of anticoagulant is needed, and there is no need to take anticoagulant drugs for a long time. As an emerging technology, “left heart ear blocking” has been increasingly used in clinical practice and has brought good news to a large number of patients with atrial fibrillation. 5. Self-management is also important. In addition to the above points, we also need to pay attention to the usual daily diet, lifestyle, exercise, etc., which are conducive to physical and mental health, strengthen the control of hypertension, hyperlipidemia, diabetes and other diseases, management of their own health, can make the prevention of stroke more effective with half the effort.