Vaginal bleeding will occur 3-7 days after taking Eusemide. This vaginal bleeding is also menstruation, but the drug is artificially used to change the thickness of the endometrium, so that the endometrium will shed and bleed when the drug is stopped. If you have irregular menstruation or irregular vaginal bleeding, you can take Eusemide orally to treat it, but only under the guidance of a doctor. You should also exclude any diseases before taking Eusebio, such as thrombotic tendency, hypertension, or uterine fibroids.