A tingling sensation in the urethra when going to the restroom is most likely to have a UTI. Further examination is needed, for example, you can do routine urinalysis or check the mycoplasma and chlamydia in the urine, and you can judge the severity of urethritis based on the leukocytes in the routine urinalysis. If the white blood cells in the urine routine are less than or equal to one plus, it proves that it is a mild urinary tract infection, and simple antibiotics can be used for anti-infection treatment. If the white blood cells in the urine routine are equal to two plus, it proves to be a moderate UTI, and a second-generation cephalosporin or second-generation quinolone antibiotic can be used. If the white blood cells in the urine routine are greater than three plus, it may be a severe UTI, and it is necessary to use the third generation of cephalosporins or the third generation of quinolone antibiotics for anti-infection treatment.