Patient: Description (onset, main symptoms, hospital visited, etc.): Patient female, 74 years old, history of hypertension, coronary heart disease, atrial fibrillation for many years, history of Parkinson’s disease for 8 years, septic appendicitis three years ago for open abdominal drainage, after healing, there is occasional abdominal pain on weekdays, which can be relieved by itself. His blood pressure is controlled at about 150/90, and Parkinson’s is usually controlled by medopa, and he takes aspirin enteric tablets on weekdays. This time, his condition: On October 24, he underwent open surgery for intestinal obstruction, and was found to have intestinal necrosis. The abdomen was bulging and drooping, the platelets were low (details unknown), the fever was 37.8-38.7 degrees Celsius, the patient did not wake up when called, occasionally responded to sound, both upper limbs were flexed, the muscle tone was elevated, the diet was nasal fluid, the stool was not clear (no gastrointestinal motility drugs were used), and a small amount of residue could be removed by enema. Sputum was aspirated in small amounts and white in color. On October 19, he developed chest tightness and panic attacks due to mood swings, and needed to be bedridden. He was transferred to Heze Municipal Hospital on the 24th for surgery and was admitted to the ICU, with daily enemas and fecal enemas on the tenth day, during which he had a lung infection with levofloxacin, cefepime, and an imported carbapenem, etc., and an albumin transfusion almost every day. One platelet transfusion, bronchoscopic aspiration, etc. His mental state changed from cognitive to unconscious, and the skin on the palm was dry and brown. In the past five days, she has been feverish, and after being admitted to the hospital, she has been adjusted with antibacterial medication from 38.7 to 37.8 degrees, but she still has edema in the prolapse area and is on a ventilator. Is there any way to bring my grandmother’s fever down? What further treatment is needed since the condition has been recurring for so long? Thank you, doctor! Cheng Li, Department of Gastrointestinal Surgery, Shandong Provincial Hospital: The patient’s condition is critical, with many comorbidities, and the outlook is not very optimistic. Look at the diagnosis and treatment process, estimated to be mesenteric vascular embolism, the onset of atrial fibrillation heart thrombus dislodgement. Once experienced the process of infectious shock, there is kidney damage, and then the long-term vascular lesions have long existed potential kidney damage, intestinal necrosis only aggravated the lesions. In the present case, dehydration may be present, and treatment should not be confined to conventional management. Fluid therapy and proper alkalinization of body fluids may help the patient’s recovery, with an estimated ex vivo exchange of up to 12% of body weight. It is important to trust the good intentions of the doctor, and it is in the presence of full trust that the doctor’s wisdom can be brought to bear. I never treat people with doubts and suspicions beyond the norm, because the extraordinary method is somewhat beyond the treatment convention and will have nothing to say after the dispute arises. Patient: Thank you Dr. Cheng! Liquid therapy do you mean dialysis? It seems to have been done. We continue to fully support the treatment.