Pediatric cerebral palsy is also known as pediatric cerebral palsy. It is a permanent but variable abnormality of movement and posture that is based on non-progressive lesions of the brain that occur between the mother’s gestation period and the child’s neonatal period for various reasons. Pediatric cerebral palsy is a very common pediatric brain disorder that can be caused by many causes. So what exactly are the causes of pediatric palsy? The direct causes of cerebral palsy are brain injury and defects in brain development. According to the time when the injury occurs, it can be simply divided into injuries during the mother’s gestation period, perinatal period and a short time after birth (usually within 1 month). 1. Genetic factors: Recent studies have concluded that genetic factors are becoming increasingly important in the influence of cerebral palsy. In a comparative study, it was found that close relatives with 2 of epilepsy, cerebral palsy and low intelligence accounted for 65% of cerebral palsy;. Fertilized eggs contain DNA genetic material from both parents, which comprise genes arranged on chromosomes. When chromosomes have numerical or structural aberrations, mutations or congenital metabolic defects they can produce congenital malformations and show abnormal development of the individual, which is likely to show symptoms of cerebral palsy. 2. Pregnancy factors of cerebral palsy: (1) Maternal infections such as rubella, cytomegalovirus and syphilis during the embryonic period. The infection invades the fetus through the placenta to produce congenital infection and malformation. (2) Environmental factors at the time of gestation: The embryo is susceptible to external environmental factors such as physical, chemical or biological factors during its development in the maternal uterus, and is especially sensitive to embryos up to 8 weeks of age. These factors can cause impaired differentiation and development of the embryo, resulting in the birth of a child with cerebral palsy. (3) Other maternal causes: including maternal abdominal trauma, maternal pre-eclampsia, prenatal hemorrhage, pregnancy toxemia, placental causes (placenta abruptio, placenta praevia, placental necrosis or placental dysfunction), and certain chronic diseases of pregnant women (such as hypertension, hepatitis, diabetes, drug addiction, drug allergy, etc.) may cause the occurrence of pediatric cerebral palsy symptoms. 3. Neonatal factors of cerebral palsy: Convulsions in the neonatal period are the most important risk factors for cerebral palsy. Birth weight <;2500g, the need for special care and the presence of inhibition in the neonatal period are important factors for cerebral palsy; respiratory distress syndrome, aspiration pneumonia, sepsis and meningitis in the neonatal period are significantly associated with cerebral palsy; periventricular leukomalacia in premature infants, asphyxia at birth with hypoxic-ischemic encephalopathy are important causes of lasting brain damage; immature infants with asphyxia sometimes present with specific lesions such as ventricular hemorrhage and periventricular leukomalacia, which can be the cause of cerebral palsy. Injury to the pediatric brain during delivery, cranial injury or brain infection in newborns, and cerebrovascular accidents can also lead to cerebral palsy in children. 4. Physical factors: The most common physical teratogenic factors causing cerebral palsy are: rays, mechanical factors, high temperature, cold, microwaves, lack of oxygen, etc. Overall, prenatal causes of cerebral palsy account for about 20%, perinatal and delivery causes account for 70%-80%, and postnatal causes are 15%-20%. It is generally believed that asphyxia, immaturity and severe jaundice are the three main causative factors of cerebral palsy. However, in recent years, the percentage of prenatal cerebral palsy has tended to increase due to a decrease in severe jaundice as well as cerebral palsy caused by immature infants. Therefore, parents must pay attention if their children have the above high-risk factors. Take your child for regular medical checkups and observe your child for any corresponding abnormal signs in your life. In case of abnormalities, you should visit a child health care or rehabilitation clinic as soon as possible.